- Get the details on Anasarca

POEMS syndrome

POEMS syndrome (PS) is an uncommon medical condition, but when it does occur, it can be a medical reason behind anasarca. PS is more common among men than women, impacting them at a rate of around two to one.


There is a range of medical symptoms and signs that might appear in someone with PS. Often, polyneuropathy is involved. In this disorder, a number of the patient's peripheral nerves at locations around the body are affected at once -- failing to function as normal. An unusual enlargement of organs can also affect the person. Damage to the endocrine system is another possibility, and this can lead to various medical issues, including low production of thyroid hormone, type 2 diabetes, and many more.

Edema, or fluid accumulation leading to swelling, is another possibility. This is where anasarca fits in the picture as something that can result from POEMS syndrome. Myeloma can also appear, occurring in over fifty percent of patients with this disease. Additionally, changes in the patient's skin might be noticed -- for instance, a darkening of a portion of the skin, known as hyperpigmentation, can be such a symptom.


A set of criteria is used to make a diagnosis of PS. The doctor involved takes such information into account to make a determination of whether or not to diagnose this particular condition. If the criteria for diagnosis is not met, then perhaps there is some other issue that is affecting the individual, which simply does not qualify under the current understanding of POEMS syndrome.


A person who is medically qualified is the one who prescribes a specific treatment method for the patient affected by POEMS syndrome. There are different options which may be considered. Treatment needs to be focused at the underlying blood disorder, although treatment for relief the symptoms may also be possible.

Other medical causes of anasarca

Read more about additional medical reasons for anasarca, or go to the home page for general information abxout the condition.

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