Certain underlying medical causes can bring on a case of anasarca in a patient. Several of the possibilities are considered on this page, with quick details covered on each of these potential causes.
Congestive heart failure
, also known as congestive cardiac failure, is commonly brought on by low cardiac output. However, it can also happen when the body requires more nutrients and oxygen, and the heart does not supply it as quickly as the body needs. The latter situation may take place in certain conditions, for example, hyperthyroidism, Paget's disease, and severe anemia, to name a few.
, due to cirrhosis
- In this case, the cirrhosis of the liver finally leads to its failure. Cirrhosis can also lead to a variety of other complications aside from liver failure (and the potential anasarca resulting from that). Numerous medical causes can lead to cirrhosis, but several of those possibilities include: alcoholic liver disease (ALD), chronic hepatitis B or C, autoimmune hepatitis, and Non-alcoholic steatohepatitis (NASH).
, known as nephropathy, can lead to anasarca. It can be caused by chronic issues such as high blood pressure, diabetes mellitus, and systemic lupus erythematosus (SLE), as well as exposure to lead or lead salts, and xanthinuria (xanthine oxidase deficiency), amongst other items. The condition is sometimes known by its previous name, nephrosis.
is another potential anasarca cause. Malnutrition of particular vitamins, minerals, nutrients, and various essential items can lead to different medical problems, based upon the type of deficiency. For instance, a vitamin B12 deficiency can cause pernicious anemia. Malnutrition of any specific thing may not necessarily lead to anasarca. A severe protein deficiency is one possibility that can result in such a condition.
Systemic capillary leak syndrome, also known as Clarkson syndrome, can cause generalized swelling. The condition is rare. In it, the pores in the blood capillaries increase in size and in count. This causes fluid to leak from the blood and into the interstitial fluid. Swelling, decreased blood pressure, and failure of multiple organs can follow.
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